Why Are Diseases Of Affluence & Age Rising?

Kate Jeffrey

The incidences of chronic inflammatory diseases such as allergies, arthritis, and diabetes are dramatically rising in western industrialized societies at alarming rates. Genetics alone cannot explain this increase in diseases resulting from mistakes made by our billion-year-old immune system. Kate Jeffrey, Assistant Professor in Immunology at Massachusetts General Hospital and Harvard Medical School, explains how environmentally driven changes in our epigenome, the interface of our genes and environment, is a possible cause and drug discovery target for these diseases of affluence and age.

Kate Jeffrey

Kate Jeffrey is an Assistant Professor of Medicine at Harvard Medical School, an Assistant in Immunology at Massachusetts General Hospital, Faculty of Harvard Immunology, Faculty of Harvard Virology, and an associate member of the Broad Institute of MIT & Harvard. Her research focuses on the epigenomic regulation of innate immunity in health and disease. Her work established inhibitors of epigenetic enzymes as anti-inflammatory agents and she recently was the first to describe a loss of an epigenetic enzyme in patients with inflammatory bowel disease. Kate is also co-founder of the New York Imagine Science Film Festival in New York and is a proud mother of two daughters.
Full Bio