Are Infections Causing Alzheimer’s Disease?

Robert Moir

Over 50 million people worldwide suffer from Alzheimer’s disease (AD), which is an incurable and fatal disease characterized pathologically by the accumulation of insoluble brain deposits called amyloid. Robert Moir, Assistant Professor at Massachusetts General Hospital Department of Neurology and Harvard Medical School, shares groundbreaking new research suggesting amyloid is actually an immune response that works to trap and neutralize invading pathogens. This discovery suggests infection may play a role in AD and is helping point the way towards urgently needed new treatment strategies.

Robert Moir

Robert Moir is an Assistant Professor at Massachusetts General Hospital Department of Neurology and Harvard Medical School. He is a neurobiologist whose research focus is the cause of dementia in Alzheimer's disease (AD). A decade ago he identified an unsuspected immune role for the protein thought to drive neurodegeneration in AD. His findings revealed the protein is a natural antibiotic and has since shown the protein’s antimicrobial actions result in the hallmark brain pathology that makes AD so distinct from other dementias. His discoveries suggest microbes may play a key role in AD and are challenging longstanding views on the origins of this terrible disease.
Full Bio